Sequential art, semantic superpowers, and standards compliance

The state of digital comics is strong, with new players and incumbents alike leading the charge to bring sequential art onto tablets and other devices, prompting a renaissance in readership and creator-owned content. But most approaches presuppose the shoehorning of print publications into a digital container—what does a digital-native comic look like? How does the creation and consumption of the graphic narrative form benefit from techniques like responsive design, and tools like version control systems and APIs?